RNA interference technology

RNA interference technology

Postby postdoc on Wed Jul 06, 2011 7:22 pm

RNA interference technology is emerging as a powerful tool for human therapy, which could lead to novel therapeutic developments for untreatable and severe diseases (including cancer and certain infection diseases).
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Re: RNA interference technology

Postby transfection on Sun Nov 27, 2011 2:20 pm

Therapeutic RNAi development services are offered by Altogen Labs): targeted siRNA, qPCR assays - http://altogenlabs.com/services/pre_clinical_research_services/therapeutic_sirna_development_shrna_mrna_reduction_gene_knockdown_stable_rnai
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Re: RNA interference technology

Postby biology12 on Thu Jul 03, 2014 1:08 pm

The RNAi (http://en.wikipedia.org/wiki/RNA_interference) effect was likely originally an early pathogen-identification system in the cell, performing identification and destruction of any double-stranded RNA to prevent viral replication.

Alternatively, it's been suggested that the RNAi pathway affects transcription in some way, as small RNAs may determine which genes are transcribed and which remain wrapped inside the chromatin (http://www.nature.com/horizon/rna/background/interference.html).
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